Elderly Sleep Apnea Sufferers May Live Longer

New research results suggest that sleep apnea - which has often been linked to increased rates of cardiovascular morbidity and mortality - may actually contribute to higher survival rates in the elderly. The findings by Technion-Israel Institute of Technology researchers were presented last week in Glasgow, Scotland, at the 19th Annual Congress of the European Sleep Research Society.

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Led by Prof. Peretz Lavie of the Faculty of Medicine, the study was conducted over a 4.5-year period, with researchers comparing mortality rates among elderly subjects diagnosed with sleep apnea to those of the elderly in the general population. Results were divided by to age, sex, and ethnic origin.

When mortality rates of 611 elderly patients with "light or no" sleep apnea, "moderate" sleep apnea, and "severe" sleep apnea were compared with the general population, those suffering from moderate sleep apnea had a mortality rate one-third of that of the general population. And mortality rates for the elderly with no sleep apnea, light sleep apnea and severe sleep apnea were on par with those of the general populace.

"These findings, when combined with new findings in scientific literature of the adaptive influences of intermittent hypoxia (lack of oxygen) in various clinical models, strengthens our hypothesis that sleep apnea activates defense mechanisms among the elderly that provide them with survival advantage," said Lavie.

Although sleep apnea is more prevalent among the elderly than among the young and middle-aged, the medical implications among the elderly are still not well known.

Affecting 10 percent of men and five percent of women, sleep apnea has been found to constitute a significant risk for cardiovascular morbidity and mortality. The findings from many studies - including some conducted at the Technion - show patients with sleep apnea are at a higher risk for mortality, particularly if they are overweight.

The research was conducted in the Lloyd Rigler Laboratory for Sleep Apnea Research at the Technion Faculty of Medicine.

The Technion-Israel Institute of Technology is Israel's leading science and technology university. Home to the country's winners of the Nobel Prize in science, it commands a worldwide reputation for its pioneering work in nanotechnology, computer science, biotechnology, water-resource management, materials engineering, aerospace and medicine. The majority of the founders and managers of Israel's high-tech companies are alumni. Based in New York City, the American Technion Society (ATS) is the leading American organization supporting higher education in Israel, with 22 offices around the country.


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